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medicinal chemistry approach require iteratives' synthesis steps coupled to protein-binding characterization. Biophysical characterization methods (NMR, ITC, SPR) at this stage generally involve purification
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. Experience in designing and carrying out chemical syntheses, also in anaerobic conditions. Experience in the use of analytical methods for characterization of organic and coordination compounds, including NMR
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synthesis (SPPS) · Develop and screen non-covalent and covalent peptide libraries · Perform peptide folding and stability analyses (CD spectroscopy, VT-CD) · Conduct structural studies by NMR spectroscopy
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nucleic acids and peptides and their analogues will be advantageous. Knowledge and understanding of statistical analysis and key analytical techniques (e.g., NMR spectroscopy, mass spectrometry, UV
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an emphasis on technology, data science and the humanities. Dr. Chuchu Wang’s lab is an interdisciplinary research lab integrating cryo-EM/ET, lipidomics, and NMR to study protein–lipid interactions in
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At least 70% of your assignment will be spent on academic research with the main focus on studying the structure, dynamics, and intermolecular interactions of membrane-active lipopeptides using NMR
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organometallic catalysts; the application of the developed catalysts in homogeneous catalysis; and the elucidation of reaction mechanisms using various techniques (e.g., NMR, UV-Vis, CV, IR, etc.). The goal of our
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, and Jason Widegren https://www.nist.gov/programs-projects/electric-acoustic-spectroscopy-intermolecular-interactions-solution#OnChip NIST’s Material Measurement Laboratory (MML) and Communications
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the major equipment required to characterise the organic molecules and catalysts generated as part of this project (XPS, XRD, TEM/SEM, mass spectrometry, NMR, etc.). The E2P2L (Eco-Efficient Products and
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mechanisms for apicoplast DNA compaction. In this collaborative, inter-disciplinary project, we will use cryo-EM (Lahiri lab https://sites.google.com/sheffield.ac.uk/lahirilab/), NMR (Willamson lab https