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will combine 2 and 3D cell culture systems, gastruloids development, FACS drug screening and next-generation sequencing with investigation of patient samples, to identify and characterise targetable
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, ambitious, dynamic, and well-resourced working environment. Our unit and our department have state-of-the-art facilities for flow cytometry, next generation sequencing, single-cell transcriptomics, mass
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models for clinical decision-making from EMRs and genetic sequencing data. Focus on predicting patient outcomes and discover novel biologically relevant disease subtypes. Responsibilities: Collecting
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Metagenomics (the sequencing of all genetic material within a sample) offers the promise of being a single test to diagnose all clinical infections. By directly sequencing all nucleic acid from a
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often fail to preserve the fidelity of combined datasets, leading to loss of crucial information. This proposal aligns directly with the CAMS Data Analytics Theme and the Grand Challenge of using machine
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single cell sequencing analyses of mouse and human bone marrow cells at leukemia onset, throughout the course of treatment and upon relapse. Ideally, the candidate brings in strong expertise in cell
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-cancer drugs in cancer therapy will be investigated. Antibody arrays, qRT-PCR, Western blotting assays and RNA sequencing (RNA-seq) will be employed to study the underlying mechanism of action. Finally, a
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, stakeholder alignment, and innovative business models that promote multi-value creation. You will investigate how long-term visions and transition paths can be shaped with partners, how startups and SMEs can be
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peptides, including the design of de novo sequences based on the elucidated mechanism. The first step will be to develop a computational approach to determine the critical peptide properties required
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palynology and organic biomarker and biogenic calcite geochemistry at several sediment sequences. You will collaborate with fellow PhD candidates or postdocs carrying out climate model experiments