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A senior postdoctoral fellow position is immediately available in Dr. Ranjan J. Perera’s laboratory at the Department of Oncology and Neurosurgery, Johns Hopkins University School of Medicine, and the Center for RNA Biology, Cancer & Blood Disorders Institute, Johns Hopkins All Children’s...
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functional genomics — previous experience with multiple nextgen sequencing platforms, spatial multiomics platforms, and/or a strong computational background is preferred Knowledge of aptamers, SELEX
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research program exploring: (i) the role of replication timing in cell-fate transitions; (ii) the impact of ERCE sequence variation on phenotypic traits; and/or (iii) the potential of ERCEs as tools for cell
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novel in vivo gene therapy approaches targeting hematopoietic stem cells. You will generate data on efficacy and safety of gene therapy vectors in multiple target cells and carry on preclinical
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know very little about the mechanisms that align DNA replication activities to potentially harmful endogenous threats such as metabolic stress and thereby limiting the detrimental consequences
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activities within the Experimental Neuropathology Unit. The selected candidate will contribute to the project: Title: Dissecting microglia vulnerability to stress response in Multiple Sclerosis through human
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methods to diagnose and monitor childhood cancers. This may include the use of ultra-rapid RNA-sequencing for real-time diagnostics and analysis of circulating nucleic acids to monitor drug resistance
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techniques in our laboratory, including population-scale epidemiology studies, digital pathology, genomic sequencing, and spatial transcriptomic and protein profiling. Our tissue profiling work encompasses
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to intervene the malignancies 3) collaborative analyses of myeloid cancers genomics using high-throughput single-cell sequencing chor high throughput proteomics 4) development of small molecule drugs and PROTAC
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, such as the Alzheimer’s Disease Sequencing Project and UK Biobank, and serve as the Biomarker Core for the Stanford Alzheimer’s Disease Research Center, curating and analyzing a deeply-phenotyped dementia