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molecular biology expertise in mammalian cell culture, and genome editing techniques strong analytical and problem-solving skills preferably skills in next generation sequencing-based methods and
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processes associated with CIN [1], leveraging single-cell DNA sequencing understand CIN heterogeneity [2], and development and implementation of machine learning and AI models to imaging data [3]. The student
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[Nature Biotechnology 2023, 41 1265], as well as novel approaches for the genome sequencing of modified bases and are exploring further base modifications, and how they interact with chromatin proteins (e.g
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PhD Student Brain multiregion singlecell transcriptomics of Myalgic Encephalomyelitis/CFSyndrome NIN
postmortem tissue, high-throughput sequencing, and translational neuroimmunology. You will be involved in identifying molecular targets and immune biomarkers for ME/CFS, potentially guiding future therapeutic
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proteins (RIME) in a context where PRDM9 is present or absent, and the genomic localization of its known co-factor REC114 will be studied by ChIP followed by NGS sequencing. For a better mechanistic insight
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, next-generation sequencing such as long-read sequencing, and high-throughput analysis techniques. Primary tasks: Culture human T cells and cancer cells Design multiplexed CRISPR strategies Analyse
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sequencing technologies - including metagenomics and transcriptomics - to explore the dynamic interplay between human gene expression and microbial communities. The successful candidate will develop and apply
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lengthy processing times associated with sequencing. This PhD project aims to develop innovative artificial intelligence (AI) methodologies by integrating histopathology images and RNA sequencing data
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. You will build a clinical trial-ready cohort by developing an accurate, scalable sequencing and bioinformatics pipeline, alongside genetic risk stratification, positioning Newcastle as a world leader in
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MSc/PhD Position at the Faculty of Medicine, Memorial University of Newfoundland, St. John’s, Canada
research project focused on exploring the immunometabolic pathways of macrophages and microglia in multiple sclerosis (MS). The Kaushik Lab is committed to fostering an inclusive and equitable research