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activity (2, 3). This finding was unexpected because PCPE1 and PCPE2 are very similar in terms of sequences and structures. Objectives The main objectives of the PhD project will be (i) to elucidate
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to macroevolutionary questions related to a better understanding of the tree of life, will involve the development and application of complex sequence evolution models (mixture models) and molecular dating, within both
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, the PhD student will have at his/her disposition a set more than 150 high quality genomes (assembled from long-read sequencing and polished with short-reads), more than 100 of P. destructans and more
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analyses (bioinformatic and statistical) of environment and microbiome data, including amplicon sequencing libraries, metagenomes, and metatranscriptomes. • Publish (as lead and co-author) in leading
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for degradation, the PTI response is nucleotide sequence-independent and triggered also by other dsRNA molecules, for example by exogenous treatment of plants with poly(I:C) (Niehl et al., 2016, New Phytol 211
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the T4SS, test it through functional assays, and validate it using structural approaches. Main tasks Perform genetic constructions (cloning, mutagenesis, sequencing validation) and functional bacterial
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aims to provide an integrated assessment of urban vegetation from multiple perspectives, including its social functions and usage requirements, the ecosystem health of green spaces linked to plant
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international collaborators. - Production of viruses and infection in an L3 containment laboratory - High-throughput sequencing and bioinformatics analysis - Microscopy (RNA and proteins) - CRISPR genetic
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. Good command of biostatistics (database management, use of R software) as well as an excellent level of English are essential. As eDNA data are amplified and sequenced independently, the involvement
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proteins (RIME) in a context where PRDM9 is present or absent, and the genomic localization of its known co-factor REC114 will be studied by ChIP followed by NGS sequencing. For a better mechanistic insight