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] Oligonucleotide therapeutics are an emergent drug modality and consist of modified or unmodified short nucleic acid sequences; these include antisense oligonucleotides (ASOs), small interfering RNA (siRNAs
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in RNA biology, biochemistry, and Oxford Nanopore sequencing. The Norwich Research Park Biosciences Doctoral Training Programme (NRPDTP) is offering fully funded studentships for October 2025 entry
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metagenome sequencing. The Salmonella and AMR from pigs in Brazil will be compared to publicly available data on Salmonella and AMR in humans in Brazil (through Enterobase) and in the UK (through the UKHSA
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associated with genome dominance. Transposable element distribution and activity will also be analysed using long-read sequencing. This project is primarily computational and offers comprehensive
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colon models, multiomics sequencing and bioinformatics, you will explore how ALGAFILL is processed in our gut, its effects on microbiome, metabolism, and potentially health. Culture-based molecular
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on genomic signatures, (2) use whole-genome-sequencing to discover population-level adaptation to different environmental constraints and (3) conduct enzymatic activity and gene expression experiments to test
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representatives of the Watkin’s collection for take-all suppression in the presence of different rhizosphere microbial communities conduct amplicon sequencing on the established communities to analyse how microbial
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datasets. Genome sequences are now available from half to a million people, meaning that we can expect to observe rare mutations at a large fraction of sites in the human genome. We can use this to try to
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the likely clinical outcome and aligning this with the patient’s known individual goals and preferences. The planned mixed-methods PhD will incorporate a scoping review, a data linkage study, and qualitative
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sequencing technologies - including metagenomics and transcriptomics - to explore the dynamic interplay between human gene expression and microbial communities. The successful candidate will develop and apply