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Multiple Long-Term Conditions (MLTCs). It has a particular focus on research that is highly relevant to disadvantaged communities who are most impacted by MLTCs. It is led by a multidisciplinary team of
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. This will require the application of a range of techniques, from in-vitro biochemistry to novel, next-generation sequencing approaches. Most skills can be acquired and developed throughout the post, offering
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in-house RNA sequencing datasets, the post-holder will discover common human renal and cardiac senescence biomarkers. They will also test the potential of spatial transcriptomics to measure drivers
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capability Broad understanding of next generation sequencing (NGS) technologies and demonstration of proven experience in analysis of bulk and single cell transcriptomic data would be an advantage Ability
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; Protein biochemistry; RNA-seq or whole genome-sequencing; Quantitative mass spectrometry;
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biological science, together with relevant laboratory and computational experience (flow cytometry, cell culture, molecular sub-cloning and analysis of next generation sequence data). Experience in coding and
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biological science, together with relevant laboratory and computational experience (flow cytometry, cell culture, molecular sub-cloning and analysis of next generation sequence data). Experience in coding and
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the presence of significant confounding factors Organise large-scale sequence data sets Communicate results at project meetings and conferences Present research outputs, including drafting academic publications
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to further develop technology that we have invented to assemble large DNA molecules of any sequence with ease. Using this technology, it is possible to rapidly and simply assemble DNA molecules up to hundreds
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, including integration of multimodal sequencing and 3D imaging datasets. They will be expected to produce independent and original research in this area, develop and apply new concepts and have a creative