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will be required to take a leading role across multiple projects, with support from other members of the team. Project topics are agreed with the funders in accordance with their priorities. KIS is a KHP
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be ideally be proficient with microbial genetics, molecular microbiology, basic tissue culture and molecular biology techniques. Prior experience with bioinformatics (microbial sequencing and
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will be required to take a leading role across multiple projects, with support from other members of the team. Project topics are agreed with the funders in accordance with their priorities. KIS is a KHP
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the work of others and act as team leader as required. The successful applicant will possess sufficient specialist knowledge in transcriptomics and NGS sequencing as well as the essential computational
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handling of RNA samples. Desirable: D1. Skills in gene-editing techniques such as CRISPR-Cas9 and transfection D2. Skills in library preparation for Next-Gen sequencing. D3. Skills in analysis of Next-Gen
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that conjugating siRNAs to peptides that bind receptor X will enable targeted delivery of disease-modifying agents directly to affected joint cells. This project will: 1. Identify optimal siRNA sequences
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remission as a model of flare vs remission with a 50% relapse rate. Initial data analysis has taken place using the 10x Chromium single cell sequencing identifying putative cellular subpopulations
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methodologies include cell culture, analysis of DNA damage and repair by microscopy and RNA-sequencing for splicing analysis. Main Duties The responsibilities may include some but not all of the responsibilities
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Robotics and AI Fellowship (1 position available) Strategically aligned with our EPSRC-funded Doctoral Programmes (AgriFoRwArdS Centre for Doctoral Training and Doctoral Training Partnership). Research Areas
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of seed gene networks”. This project aims to use reverse genetics, cross-species complementation and single cell next-generation sequencing approaches to investigate how the gene networks that regulate