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and mobile genetic elements in waterways. High-throughput sequencing approaches such as metagenomic sequencing will be used to study the microbial community structure, resistome diversity, and potential
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will aim to answer this, by sequencing whole genomes from the few surviving British red squirrel populations, and continental reference populations. It will also sequence historical British squirrel
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bacterial factors that predispose to higher infection morbidity including certain phylogenetic groups, sequence types and virulence factors. In this project, the student will investigate the hypothesis
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to align with their background and interests. Example topics include: Groupoid models for C*-algebras; Cartan subalgebras of C*-algebras; Semigroup C*-algebras; Ring C*-algebras; C*-algebras from algebraic
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properties. Fungi are a rich source of such compounds, with notable examples including penicillin, lovastatin, and ciclosporin. Advances in genome sequencing and bioinformatics have revealed that fungal
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considerations in topological dynamics, algebra, or group theory. The research problem will be co-created with the student to align with their background and interests. Example topics include: Groupoid models
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-and-prediction-of-cancer-evolutionary-dynamics-from-cfdna for further information. Project aims Develop a sequencing approach to detect mutations and methylation in cfDNA from cancer patients Build
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DNA sequence itself. These changes can be inherited during cell division and are particular stable in plants, where they represent the base of an epigenetic “memory”, which remains encoded in biological
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PhD Studentship - EASTBIO - The Impact of Diet-microbiome-immune Interactions on Intestinal Function
function. Microbial RNA sequencing will be used for profiling the gut microbiota and identifying functional bacterial pathways, which will be validated by manipulation (i.e. depletion and transplantation
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optimisation for plasmid production Application of LLMs to biological sequence design Microbial genetics and horizontal gene transfer Cross-disciplinary collaboration across synthetic biology, AI, and