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hybrid sequencing approaches to explore highly repetitive DNA sequence in relation to genomic instability in childhood cancer. Highly repetitive DNA is impossible to resolve using conventional short-read
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, alongside other major global pathogens including hepatitis B and C viruses, HIV, SARS-CoV-2 and Dengue. The postholder will be responsible for designing and optimising sequencing approaches, leading data
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sequencing approaches to explore highly repetitive DNA sequence in relation to genomic instability in childhood cancer. Highly repetitive DNA is impossible to resolve using conventional short-read sequencing
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and cancers. The dataset will bring together digital whole-slide pathology images, clinical photographs, genomic sequencing, and clinical outcome data, laying the foundation for AI-powered diagnostics
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with sequencing data analysis and conduct meta-analysis for pathogenic variants across multiple datasets. Supporting the interpretation of results and contributing to the writing of manuscripts
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sequencing, spatial and single-cell multi-omics. This research could deepen the fundamental knowledge and promote translational/preclinical development. You must have a proactive and adaptable approach to work
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work on the PANGEA-HIV project, analysing viral sequence data to assess how effective broadly neutralising antibodies may be against current HIV strains in Southern Africa. Second, you'll support early
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techniques for example multi-parameter flow cytometry, cell culture, systems serology, ELISpot and ELISA. You should have some knowledge of single-cell RNA sequencing (RNAseq) and other relevant next
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for example multi-parameter flow cytometry, cell culture, systems serology, ELISpot and ELISA. You should have some knowledge of single-cell RNA sequencing (RNAseq) and other relevant next generation sequencing
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into the genomics of population structure and speciation in the Malawi cichlid genus Labeotropheus. This post will build on past work in which over 1000 samples of Labeotropheus from multiple species/populations have