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the work of others and act as team leader as required. The successful applicant will possess sufficient specialist knowledge in transcriptomics and NGS sequencing as well as the essential computational
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will be required to take a leading role across multiple projects, with support from other members of the team. Project topics are agreed with the funders in accordance with their priorities. KIS is a KHP
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of quantitative genetics, performing GWAS, QTL detection, genomic prediction and previous work experience with whole genome sequence data and imputation. A prior knowledge of functional variant prioritisation
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or MSc in biological sciences or a related field and bring experience in DNA/RNA extraction, PCR-based techniques, and next-generation sequencing. A strong understanding of regulatory requirements
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handling of RNA samples. Desirable: D1. Skills in gene-editing techniques such as CRISPR-Cas9 and transfection D2. Skills in library preparation for Next-Gen sequencing. D3. Skills in analysis of Next-Gen
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and collaboratively within a team, with a strong background in human and murine primary cell culture, confocal microscopy, RNA Sequencing techniques and/or tuberculosis research. Familiarity with flow
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materials employing PCR- and ddPCR- based techniques and Nanopore sequencing Sample management and communication of results internally Other general duties required are to ensure the smooth running of a
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states of matter, which are generally characterised by their long-range quantum entanglement, fractionalised excitations, and absence of ordinary magnetic order, using multiple experimental techniques
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samples and data. The project integrates whole-genome sequencing, transcriptomics, epigenetic profiling, and clinical information to uncover the key molecular drivers that underpin tumour progression and
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that conjugating siRNAs to peptides that bind receptor X will enable targeted delivery of disease-modifying agents directly to affected joint cells. This project will: 1. Identify optimal siRNA sequences