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that may remove such constraints, leading to a fundamental challenge: the potential co-existence of genetically distinct clones, each supporting multiple stable cancer cell states. To understand the effect
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“Quantitative predictions of protein – DNA interactions from high-throughput biophysical binding data”. Sequence specific binding and recognition between transcription factors and DNA control gene expression at
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cellular techniques, such as bulk and single-cell RNA sequencing, spatial transcriptomics, immunohistochemistry, immunoprecipitation, RNA-pull down, ChIP-seq, or CRISPR/Cas9-based gene editing etc. The exact
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project: Computational methods for complex SV detection using sequencing data Main supervisor: Kristoffer Sahlin, ksahlin@math.su.se . Co-supervisor: Adam Ameur, adam.ameur@igp.uu.se . In the Department
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involves collecting clinical data on the effects of childhood cancer treatment, bioinformatically handling sequence data and developing prediction models, as well as conducting Single Cell RNASeq studies and
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-throughput sequencing of genomes and biomes, continuous recording of video and audio in the wild, high-throughput imaging of biological specimens, and large-scale remote monitoring of organisms or habitats
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components of organisms’ general life-history decisions. The work involves accumulation of mutations in different fly lines, extracting DNA and building libraries for sequencing, as well as bioinformatics
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monitoring. These applications rely on remote sensors to capture PCs and wirelessly transmit them to edge servers for downstream tasks, such as registration, i.e., aligning multiple PCs within the same 3D
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application no later than August 1, 2025. Project description Linear algebra expressions are evaluated in an efficient and robust way by mapping them to a carefully chosen sequence of calls to optimized
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beneficial – but not mandatory – if applicants demonstrate alignment with one of our research centres (described above) or faculty research strengths. We offer A fully funded position with access