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Field
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validation, and regulatory reporter assays. Learn more about the group here . YOUR MISSION: Investigate how genetic variants affect male reproductive function Perform single-nucleus and bulk RNA sequencing
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Your Job: Development and optimization of single-cell RNA sequencing protocols (10x Genomics) in plant tissues Co-development of spatial transcriptomics protocols with collaborators at CEPLAS
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of the alternative infection model Galleria mellonella .Techniques to be employed include culturomics, functional studies, cell culture, next-generation sequencing (NGS), biochemical assays, and competitive growth
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used, including cell culture methods, Next-Generation Sequencing (NGS), Omics analyses, biochemical assays, and microscopic imaging. The project will be conducted in close collaboration with Dr
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at diagnosis and relapse, and compare them to healthy hematopoietic specimens using nanopore-based direct tRNA sequencing. Complementary transcriptomic, proteomic, and metabolomic profiling will be performed
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extraction, sequencing library preparation, Hi-C, ATAC-seq etc.) Experience with bioinformatic analysis of large sequencing data sets Strong statistical skills using R Desirable: Experience with assembly
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facilities span from small (1 L) to large-scale (300 L fermenter), as well as access to sequencing facilities. GEOMAR has full access to high-resolution (cryo-) NMR facilities at Kiel University. We lead or
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) to large-scale (300 L fermenter), as well as access to sequencing facilities. GEOMAR has full access to high-resolution (cryo-) NMR facilities at Kiel University. We lead or participate multiple
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differentiation goes wrong during tumorigenesis. We also investigate tumor-specific mechanisms of transformation and growth. To understand these processes, the lab integrates single-cell sequencing, whole-genome
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Gene expression modulation CRISPR/Cas9 (including knock-out, knock-in, CRISPRa, CRISPRi, viral vector systems) Next-generation sequencing (RNA-, ATAC-, ChIP-Seq, CUT&RUN, Hi-C and others) Pulldown and