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transcriptomics and single-cell RNA sequencing on patient samples • Mining and analyzing public cancer databases (TCGA, GEO, etc.) and omics data • Inferring TLS formation and maturation stages from
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Limitation:Temporary (3 years) Contract:TV-L Your tasks Infertility affects millions worldwide, yet in many cases the genetic basis remains unknown. Instead of focusing solely on gene-by-gene sequencing, this project
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at diagnosis and relapse, and compare them to healthy hematopoietic specimens using nanopore-based direct tRNA sequencing. Complementary transcriptomic, proteomic, and metabolomic profiling will be performed
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validation, and regulatory reporter assays. Learn more about the group here . YOUR MISSION: Investigate how genetic variants affect male reproductive function Perform single-nucleus and bulk RNA sequencing
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project TARGET-AI will bring together expertise from multiple research groups to advance the state-of-the-art in combining the most advanced techniques from deep learning/AI with rigorous statistical
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the era of large population size and dense genomic data such as whole-genome sequencing, new algorithms are needed to remove the bottleneck of computational load for such a development. In the frame of a
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- and long-read sequencing; computational and statistical analyses; a good mechanistic understanding of how cells replicate their DNA and respond to DNA damage. We Offer: Excellent framework conditions
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and molecular tools (e.g., 16S rRNA gene sequencing, metagenomics, and metatranscriptomics). These interdisciplinary studies will further reveal if surfactants from glyphosate application can have
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Gene expression modulation CRISPR/Cas9 (including knock-out, knock-in, CRISPRa, CRISPRi, viral vector systems) Next-generation sequencing (RNA-, ATAC-, ChIP-Seq, CUT&RUN, Hi-C and others) Pulldown and
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Collaborative Doctoral Project (PhD Position) - AI-guided design of scaffold-free DNA nanostructures
-based digital twin, which can predict the assortment and sequence of two-dimensional all-DNA motifs required for the engineering desired tessellation patterns at the nanometer scale. We will use available