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with the latest techniques / technical equipment single-cell sequencing, including CITE-seq and CloneTracer, advanced co-culture models Possibility of doctorate Possibility of habilitation Possibility
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validation, and regulatory reporter assays. Learn more about the group here . YOUR MISSION: Investigate how genetic variants affect male reproductive function Perform single-nucleus and bulk RNA sequencing
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: Nuclear mRNA export is an essential step in eukaryotic gene expression, ensuring that mature transcripts are delivered from the nucleus to the cytoplasm for translation. Multiple challenges are faced in
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Limitation:Temporary (3 years) Contract:TV-L Your tasks Infertility affects millions worldwide, yet in many cases the genetic basis remains unknown. Instead of focusing solely on gene-by-gene sequencing, this project
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Gene expression modulation CRISPR/Cas9 (including knock-out, knock-in, CRISPRa, CRISPRi, viral vector systems) Next-generation sequencing (RNA-, ATAC-, ChIP-Seq, CUT&RUN, Hi-C and others) Pulldown and
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and molecular tools (e.g., 16S rRNA gene sequencing, metagenomics, and metatranscriptomics). These interdisciplinary studies will further reveal if surfactants from glyphosate application can have
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-solving skills preferably skills in next generation sequencing-based methods and bioinformatics/computational data analysis Benefits: international working environment with communication in English and
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Collaborative Doctoral Project (PhD Position) - AI-guided design of scaffold-free DNA nanostructures
-based digital twin, which can predict the assortment and sequence of two-dimensional all-DNA motifs required for the engineering desired tessellation patterns at the nanometer scale. We will use available
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- and long-read sequencing; computational and statistical analyses; a good mechanistic understanding of how cells replicate their DNA and respond to DNA damage. We Offer: Excellent framework conditions
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analysis, next-generation sequencing, and small animal models. Salary and social benefits will be determined by the regulations of the German TV-AVH (salary agreement for public service employees