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-regulatory elements typically reduce translation of the primary coding sequence, whereas proteoforms are different protein isoforms translated from the same gene. This project aims to enhance both molecular
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short- and long-read whole genome sequencing datasets. This position provides the opportunity to develop and apply advanced bioinformatics tools and conduct innovative analyses, including integrating long
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the Sleegers lab specializes in Alzheimer’s Disease (AD), both leveraging next-generation sequencing and innovative biostatistical approaches. About the project FTD and AD are devastating neurodegenerative
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models for multivariate extremes) proposed a novel modelling framework based on regular vine tree sequences called X-vines. These models can easily be built in arbitrary dimensions by combining bivariate
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not limited to: DNA isolation, cloning and sequencing (including traditional Sanger sequencing and high throughput genomic sequencing), quantitative PCR, protein isolation and detection, RNAseq, and
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models. By utilizing biobanks of lung biopsies and established animal models, LifeLUNG will apply advanced machine learning and AI-driven deep sequencing to identify key immune factors and gene targets
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subsystems, connectivity, security features, and power management. This requires establishing clear architectural guidelines aligned with imec’s technology roadmaps and stakeholders. You’ll lead architectural
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multiple sclerosis (MS) and Alzheimer’s Disease (AD). These lipid-loaded microglia are associated with disease pathology and enhance neuroinflammation, myelin breakdown, and neuronal loss. Although brain
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and cell-molecular techniques, including multi-parameter flow cytometry and single-cell RNA sequencing. The final objective of the research is to obtain a PhD. WHAT WE ARE LOOKING FOR You hold a
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with the Department of Clinical Biology/Microbiology Diseases at UZ Brussel, sequencing platform BRIGHTcore and the AI Lab at the VUB. You will play a key role in the development of a novel AI-guided