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the molecular mechanisms underlying disease progression and treatment resistance and identify novel therapeutic targets. You will take a lead on development of computational approaches to integrate multi-omics
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remains poorly understood. It is also unclear how the conformational landscape of dynein-2 is affected by diseases mutations. This project involves using a multi-scale structural biology approach, involving
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), based at the Centre for Human Genetics, University of Oxford. The post aims to assist with the preparation and molecular characterisation of tumours using multi-omic analysis focusing principally
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-dimensional statistics; nonparametric statistics; foundations of statistics and decision theory; applied statistics, with specific attention to large-scale applications in a wide variety of contexts
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process. Algorithms will in the first instance be designed for radio astronomy and validated at extreme scales, leveraging dedicated high-performance computing implementations. Technology transfer