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work on the molecular genetics of age-related hearing loss (https://www.grilletlab.com/). The Grillet lab has generated a mouse model carrying a polymorphism identified in Genome Wide Association Studies
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are associated with neurodegenerative diseases. The Martens lab studies the interaction of the autophagy machinery with these protein substrates in cellular models and reconstituted systems. The group is based
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of epilepsy or seizure disorders using murine models and human patients. The Postdoctoral Associate will perform small animal surgeries, molecular, cellular and electrophysiological experiments with the goal
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. Advanced cell and mitochondrial biology: primary human fibroblasts, mitochondrial bioenergetics, import assays, respiratory chain phenotyping, in vivo disease models. Multi‑omics: single‑cell and bulk
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Database (Nanograindb; in development). These three databases will enable the study and interpretation of spectral signatures from carbon in the interstellar medium—including molecular clouds, planetary
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dynamics during regeneration, aging, and cancer, and how these processes can be modulated. Our research is primarily conducted in vivo. We combine genetic mouse models (lineage tracing, conditional
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their EVs stimulate or regulate immune responses. They will also investigate if EVs can be used for cancer immunotherapy. The studies will be performed in model systems in vitro and in vivo. The studies will
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Université Paris-Saclay GS Biosphera - Biologie, Société, Ecologie & Environnement, Ressources, Agriculture & Alimentation | Gif sur Yvette, le de France | France | 6 days ago
and intensity of climatic stresses. The ability of apple trees to cope with these constraints relies on a complex interplay between phenotypic plasticity, molecular regulation, and genomic constraints
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surgical animal models. Responsibilities include contributing to experimental design, supervising in vivo and molecular studies, mentoring trainees, and participating in scientific publications and research
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, to create a responsible and innovative university to serve as a model for the 21st century. Within ICN, the ChemSenSim group (https://lab.chemsensim.fr/ ) develops interdisciplinary research projects