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currently has multiple extramural grants from both the National Institutes of Health and the Veterans Administration. These grants focus on advancing two specific molecular mechanisms, RNA splicing and lipid
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: Immunology, Animal Modeling, and Pathogen Unit. These units directly support resident DHVI/RBL faculty and are also available to support Duke faculty and their collaborators as fee-for-service shared
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microscopy and atomic force microscopy. Molecular cell biology, animal models, MRI imaging, transcriptomics. References Plaisier E, et al. Role of COL4A1 Mutations in the Hereditary Angiopathy with Nephropathy
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conditions of the gut, using in vivo, ex vivo, and in vitro model systems. This position will assist with proper maintenance of lab safety documents and overall compliance of regulatory requirements. Position
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advanced optical neurotechnologies that have enabled large-scale optical interrogation of neuronal population activity at high spatiotemporal resolution across model systems. These capabilities have opened
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skills in general and a taste for meticulousness are essential. In parallel, interest for soft matter concepts and modelling will be of help to interpret the data. Experience in data analysis (including
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of novel tumor-inhibiting compounds and therapy resistance mechanisms in human cell models. Characterization of bioactivities by cell and molecular biology-based methods including flow cytometry, (confocal
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model for innovative medical education and a centre for transformative research. The School’s primary clinical partner is the National Healthcare Group, a leader in public healthcare recognised
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dedicated to elucidating the cellular and molecular mechanisms that establish immune tolerance to the microbiota, exploring how dysregulation of these pathways contributes to diseases and disorders in the gut
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the molecular signatures of proteostasis loss and identify early markers of proteostatic failure. The role combines wet-lab spatial biology with computational approaches. You will work across models and scales