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Field
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relevant large animal model of cerebral vascular disease and blood-brain barrier disruption caused by epileptic seizures and hypoxia-asphyxia. Placing particular emphasis on endogenous antioxidant
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experiments using magnetogenetics to selectively control neurons and astrocytes in Alzheimer’s disease models, in vitro and in vivo . Perform in vivo two-photon imaging, electrophysiology, and behavioral tests
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strengths in laboratory-based enquiry using molecular genetics, metagenomics, biochemistry, cell biology, bioinformatics and structural biology, with rich clinical resources in microbiology, virology
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culture experiments (in vitro), followed by experiments using murine models (in vivo ). Your profile • You obtained a PhD degree in cell biology (or equivalent) in the past 12 months and have a strong
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project dedicated to decoding early human embryo development through cutting-edge stem cell-based embryo models, single-cell omics, with a focus on X-chromosome inactivation and cell fate. The project
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and focuses on molecular immunology and inflammatory mechanisms. Cutting-edge research models (eg. primary cell/organoid cultures, mouse models and human clinical samples) and technologies (e.g. scRNA
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investigated. These interface models and characteristics will then be transferred to other researchers for larger-scale modelling (molecular dynamics, finite element modelling of the battery…). The post-doc
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, biomechanics, single cell-analyses, advanced imaging, and animal models. Tasks: to actively pursue the proposed project with the aim of characterizing the molecular, biomechanical and functional mechanisms
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. The position will involve the use of molecular tools to generate transgenic parasites, advanced imaging techniques and the implementation of new chemoproteomic protocols. Parasite culture, biochemistry and
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Schizosaccharomyces pombe as a model organism. Representative publications include: Nature (2011), PMID: 21725325; Molecular Cell (2016), PMID: 27666591; Cell Reports (2016), PMID: 26832414; PNAS (2021), PMID