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Cambridge Institute (CRUK CI), to investigate the molecular mechanisms of small RNA-mediated chromatin silencing. As a whole, the Hannon laboratory has broad interests that range from discovery research
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: Advanced molecular and protein analysis Mass spectrometry-based imaging Multi-omics technologies Preclinical cardiometabolic animal models They will also gain professional development in data stewardship
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tumours and metastases with the goal to design combinatorial therapeutic approaches. The project will involve the use of genetically complex organoid-derived transplantation mouse models of pancreatic
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on cell viability and DDR activation in established human cell models. The student will perform CRISPR screens to determine factors that affect resistance/sensitivity and follow these up with mechanistic
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cells or the tumor microenvironment reduces tumor growth and extends survival in preclinical models, underscoring their potential as dual-function therapeutic targets. To address this, we aim to develop
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at the point of commencing this post, with experience in contemporary molecular cell biology, tumour metabolism, experimental modelling and bioinformatics as applied to translational cancer genomics, ideally
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, with experience in contemporary molecular cell biology, tumour metabolism, experimental modelling and bioinformatics as applied to translational cancer genomics, ideally within the context of childhood
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manufacturing (3D printing) techniques. The purpose of the studentship is to develop a next-generation in vitro model of aged human skin to evaluate the cytocompatibility of materials used in maxillofacial
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in genotyping, molecular biology and Drosophila work. CDN has close partnership with the Medical Research Council (MRC) and CDN researchers, together with clinical researchers from King’s, make up
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cross-disciplinary in nature, building skills in molecular biology, bioinformatics, ecological mathematical modelling, algal physiology and cultivation. We are looking for a highly self-motivated