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Field
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involves analyzing postmortem human brain tissue from individuals with acquired or genetic obesity to identify molecular signatures linked to obesity and weight loss. Promising microglial and neuronal
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cartilage-on-chip model specifically designed for precision medicine in osteoarthritis (OA), the most common degenerative joint disease affecting more than 1.5 million Dutch citizens. To study OA patient
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-subject clinical and pathological information with morphological and molecular knowledge of induced pluripotent stem cells (iPSC) of PD(D)/DLB patients to identify molecular profiles and drug targets. We
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Vacancies Postdoctoral position: A CARtilage on CHIP model for precision medicine in osteoarthritis (CARCHIP) Key takeaways CARCHIP will combine the expertise of the University of Twente (UTwente
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dilemma that hampers drug development, here, we implemented a translational approach that integrates within-subject clinical and pathological information with morphological and molecular knowledge
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Postdoc in Extracellular Vesicles as Mediators of Gut-Microbiome Interactions in Parkinson's Disease
to ileostomy samples, Parkinson’s disease cohorts, and novel hydrogel/motility models. This approach allows us to reveal microbial processes that are difficult to capture with standard models, connecting patient
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tracers. Specifically, you will use clinical molecular imaging data in combination with numerous methods (i.e., AI image analyses, PBPK modeling, immunohistochemistry, FACS). As a postdoctoral researcher
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of RNA therapeutics for the brain. The successful candidate will work at the interface of molecular biology, cell models of the blood–brain barrier, and advanced human in vitro systems such as induced
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Postdoc in Extracellular Vesicles as Mediators of Gut-Microbiome Interactions in Parkinson's Disease
microbiome function in health and disease. We focus on the small intestine (ileum) and colon, using access to ileostomy samples, Parkinson’s disease cohorts, and novel hydrogel/motility models. This approach
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You will develop and validate advanced AI models that integrate medical imaging, multi-modal clinical and omics data, and explainable AI (XAI) for the prediction of hepatocellular carcinoma (HCC