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cellular signaling remains a key challenge in biology and is at the heart of the project. The PhD student will be in charge of the molecular modelling aspects of the multi-scale approaches undertaken by
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-/- strain) mimicking the characteristics of AS, to evaluate the effect of DNM3OS inhibition on disease progression; (2) Cellular models to dissect the signaling pathways and molecular mechanisms underlying
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, the process of host infection remains poorly understood at the molecular level. The fd phage, which specifically infects Escherichia coli, has been used as a model for studying these viruses. This phage
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" team is located within UMR 5242, at the Institute of Functional Genomics of Lyon (IGFL). It is a multidisciplinary institute, offering interesting exposure to several system models around common themes
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researchers addressing complementary topics and methodology such as Thermodynamic modelling of multi-component planetary degassing/ingassing, Molecular Dynamic simulations of silicate melts, Petrology
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, Birkbeck), the Protim proteomics platform, and the HPC Jean-Zay supercomputer (GENCI). Title Deciphering the molecular mechanisms of substrate recruitment in the Type IV Secretion System using
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, The Netherlands) in the lab of Dorota Durek to test an engineered protease inhibitor in an in vitro model of skin scarring. More information on the scientific project is available here: Titre: Elucidation
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to study the molecular and cellular mechanisms involved in brain activity. The Institute develops innovative methods in imaging, chemistry, physiology and computer science. As part of Bordeaux Neurocampus
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supervised by Nadine Laguette (Institute of Molecular Genetics of Montpellier – IGMM, Montpellier). The Institute of Molecular Genetics of Montpellier (IGMM) is a joint research unit of the CNRS and the
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wide range of scientific skills, with each supervisor covering a specific area of expertise (DFT and Thermodynamics, Kinetics, Molecular Dynamics and ML potentials). The candiadte will contribute to a