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mutant protein in atomic detail and optimising its application to identify new ATXN3-binding molecules (warheads) for experimental evaluation. The plan will involve: a) Model Preparation, Molecular
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molecular model-ing studies at varying levels of precision: • using force field (MF) modeling for interaction models between the target enzyme and different substrates; • using Quantum/Classical Mixed Method
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and quality‑controlled, generating high‑quality serological, molecular and genomic data alongside metadata that will feed dashboards as well as catalytic and phylodynamic models. The post includes
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information with molecular genetics, environmental/lifestyle data and registry data. This work is based on intensive local, national and international collaborations. We offer a creative and inspiring
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supervisors for reference (please do not attach generic reference letters, but contact details instead). Where to apply Website https://jobrxiv.org/job/the-international-institute-of-molecular-mechanisms-277
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activities in our department range from clinical pharmacology, systems pharmacology, to basic molecular and cellular pharmacology. More information on the department is available at http://medicine.nus.edu.sg
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The International Max Planck Research School for Molecular Plant Science (IMPRS MolPlant) is a doctoral programme in plant science at the Max Planck Institute of Molecular Plant Physiology and the
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research aims to increase our understanding of somatic mutations and their functional relevance in the development of age-related diseases, see link for more information https://ki.se/en/research/research
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team, and have a strong ability to multitask Experience working in rodent models, microscopy, histological preparation of tissues, and wet lab techniques including molecular/cellular biology
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work that span from molecular, cell- and organ-based studies in humans and animal models, research conducted in the Wang Lab focuses on understanding solute carrier (SLC) and ATP-binding cassette (ABC