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-scale screens to study fundamental principles in molecular and complex trait genetics using microbes as model systems. Our core technology MAGESTIC (https://doi.org/10.1038/nbt.4137 ), a CRISPR/Cas9-based
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assess their responses by cellular and molecular biology techniques;Establish and characterise human iPSC-derived cell models, including 3D cultures and organoids for musculoskeletal disease research
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modeling. Experience in cell culture, molecular cloning, and bioinformatics analyses is required. Proficiency in statistics and programming are highly meriting, especially in gene regulatory networks
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injection, ion transfer, and structural dynamics in realistic and model systems for battery materials. The position will span experimental efforts at large scale X-ray facilities, handling and reduction
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uniquely conserved—TRIM in animals and polyD/E in eukaryotes—setting them apart from classical PQC mechanisms. We are exploring their molecular mechanisms, their roles in aging and neurodegenerative diseases
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will develop innovative and generalizable methods and tools that can be applied to the in-house molecular data in pediatric cancers, such as pediatric CNS tumors and leukemias. St. Jude leads the largest
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on the development of anti-infective drugs and vaccines using the pig as a model platform. Main tasks will include the design, coordination, and execution of pig experiments, and assessment of drug and vaccine
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of heart disease Your studies will take advantage of in vitro and in vivo pre-clinical models, including hiPSC-derived systems The postdoctoral project will combine experimental (wet-lab) and computational
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analyzing whole organism models (zebrafish and mouse) to dissect the pathophysiology of a recently identified rare pediatric neurometabolic disorder. The approach involves mainly deep longitudinal phenotyping
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Nature Careers | Vancouver South Shaughnessy NW Oakridge NE Kerrisdale SE Arbutus Ridge, British Columbia | Canada | about 2 months ago
tumor suppressor and complement inhibitor CSMD3. The successful candidate will join a dynamic and collaborative team dedicated to advancing the molecular understanding of cancer development and