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-lab-taosheng.html ) studies: (1) the chemical regulation of nuclear xenobiotic receptors, (2) the molecular basis of signal crosstalk among nuclear receptors, and (3) the mechanism of selective
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) as models. PXR and CAR transcriptionally regulate cytochrome P450 3A4 (CYP3A4) and CYP3A5-drug-metabolizing enzymes that metabolize more than 50% of clinical drugs, the dysregulation of which
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studies on scaffolds and in vivo testing in disease models; maintaining accurate and organized experimental records; presenting findings at national and international conferences; preparing manuscripts
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models recapitulating aspects of neural-microglia interactions in neurodegenerative diseases at Ghent University. Lipid accumulation in microglia is a hallmark of neurodegenerative diseases such as
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. Working experience using transgenic/knockout and xenograft mouse models, Cell Signaling and basic molecular biology techniques is valuable; familiarity with CRSPR/Cas9, cancer stem cells, bioinformatics
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mechanisms of lung transplant tolerance. It was the first laboratory to describe the mouse model of orthotopic vascularized lung transplantation and has made seminal discoveries contributing to unique
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | 21 days ago
postdoctoral research associates to perform basic and translational research in the laboratories of Drs. Angela Wahl, Martina Kovarova and J. Victor Garcia, Institute for Global Health and Infectious Diseases