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Field
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embryo. Cytokinesis, the division of one cell into two, is crucial for an organism's development and healthy life. Similarities in the structural and molecular organization of the division apparatus in a
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mechanistic understanding of polar lobe formation at the molecular, cellular and biophysical level. You will adapt live imaging, genetic and molecular manipulation, and biophysics assays to embryos of several
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embryo. Cytokinesis, the division of one cell into two, is crucial for an organism’s development and healthy life. Similarities in the structural and molecular organization of the division apparatus in a
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characteristics of obligate intracellular bacteria, including Ehrlichia and Neorickettsia spp. We use a mouse model to study the disease pathogenesis in the mammalian hosts. We also work with blood samples
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modelling of the C. elegans neural network. The lab also uses Two Electrode Voltage Clamp (TEVC) electrophysiology and molecular biology techniques to characterise receptors. There are a broad range of
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, BRCA2, and PALB2. Through advanced single cell genomics, in vivo modelling, and immune profiling, the team will study early molecular and cellular changes that occur in high-risk breast tissue. The team
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of obligate intracellular bacteria, including Ehrlichia and Neorickettsia spp. We use a mouse model to study the disease pathogenesis in the mammalian hosts. We also work with blood samples collected from
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The University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | about 1 month ago
of toxicants may also be a component of this position. The studies utilize molecular and cell biological technologies, including single cell RNAseq/CITEseq, bulk RNA profiling and qPCR, spatial biology, flow
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spinal cord as a model system. You will engage a systematic strategy to identify these mechanisms by generating innovative mouse genetic strains, identifying embryonic defects and the underlying molecular
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variants High-resolution cryo-EM and cryo-ET imaging to resolve molecular structure and guide engineering Protein design and molecular modeling, supported by AI tools such as AlphaFold2 Development