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Field
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with many opportunities for professional development and global networking. Responsibilities and qualifications We are seeking a PhD student with background and interest in enzymology, molecular biology
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supervising studies that involve in vitro assays and in vivo mouse tumor models to understand mechanisms of immunotherapy resistance, exploration of pathways involved in signal transduction in different T cell
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they release their toxic cargo to kill the cancer cells. Methods include, but are not limited to, in vitro culture of primary human cells and cell lines, organ-on-chip models, molecular biology, diverse
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TZ complexes, you are expected to determine the molecular structure and function of a TZ sub-complex consisting of 3-5 proteins. You will monitor the gating mechanism of TZ in cellular models such as
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summary and responsibilities Define the role of primary cilia in glial cells in development and disease, using both mouse models and human cells. Analyze data from molecular, genetic, imaging, and
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and stem cell biology. The study investigates how APOE4 expression in endothelial cells affects oligodendrocyte progenitor cells (OPCs), using iPSC-derived 3D co-culture models. This work aims to
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contribute to ongoing cancer risk modelling projects within the Centre for Cancer Genetic Epidemiology (CCGE), based in the Department of Public Health and Primary Care. They should have a strong understanding
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molecular mechanisms that drive its invasive behavior, both general and patient-specific. Using cutting-edge spatial techniques and CRISPR-based methods, we build data-driven models that link gene regulation
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single mirror image forms is often denoted as “A Signature of Life”. Homochirality is essential for, e.g., molecular recognition and information processing, enzyme functioning and cell replication. However
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) uses data, computational methods and artificial intelligence to study biological systems and processes at all levels, from molecular structures and cellular processes to human health and global