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Field
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, such as molecular data (e.g. omics), imaging, electronic health care records, longitudinal patient and population registries and biobanks. To be a doctoral student means to devote oneself to a research
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in the elderly as well as increased susceptibility to infections and cancers [1]. While age-related immune dysfunction has been extensively studied, underpinning the molecular changes that drive
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they release their toxic cargo to kill the cancer cells. Methods include, but are not limited to, in vitro culture of primary human cells and cell lines, organ-on-chip models, molecular biology, diverse
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help manage and contribute to our program in ex vivo human cell biology and in vivo rodent models, focused on deciphering the cellular and molecular basis for neurodegenerative diseases, including
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a result of microphase segregation. Low crosslinking regions can be weakly attached to the rest of the paint making them prone to degrade. This project will use state of the art molecular modelling
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validate the identified key (epi)genetic molecular and explore their therapeutic potential in vitro and in vivo disease models. Profile The candidate should: have an MSc in Systems Biology, Molecular Biology
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TZ complexes, you are expected to determine the molecular structure and function of a TZ sub-complex consisting of 3-5 proteins. You will monitor the gating mechanism of TZ in cellular models such as
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summary and responsibilities Define the role of primary cilia in glial cells in development and disease, using both mouse models and human cells. Analyze data from molecular, genetic, imaging, and
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against cardiac diseases. It is based on extensive preliminary work by our working group, which has demonstrated therapeutic effects of the synthetic peptide in chronic and acute heart failure animal models
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. in microbiology, immunology, systems biology, molecular biology, computational biology, or a related field. • Experience in one or more of the following areas: microbiome research, animal models