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to “trick” resistant strains into becoming drug-sensitive. This interdisciplinary research combines synthetic biology, molecular biology, and biochemical engineering to pioneer sustainable, non
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language model (LLM)-based genome design tools with bioprocess engineering to create next-generation therapeutic conjugative plasmids. These engineered plasmids will be optimised for industrial-scale
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). Design and fabricate patterned surfaces optimised for enzyme immobilisation. Assess synergistic antibiofilm efficacy under static and dynamic (flow-based) biofilm models. Apply advanced microscopy, protein
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