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spectroscopy and HPLC), organic synthesis, electrochemistry, hydrogel soft matter and modelling. You will be mentored by Dr. Maguire and will learn how to design and manage projects, how to conduct research, how
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molecular mechanisms that drive its invasive behavior, both general and patient-specific. Using cutting-edge spatial techniques and CRISPR-based methods, we build data-driven models that link gene regulation
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and stem cell biology. The study investigates how APOE4 expression in endothelial cells affects oligodendrocyte progenitor cells (OPCs), using iPSC-derived 3D co-culture models. This work aims to
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molecular interactions between ICB and γδ T cells. Position 2 will focus on the potential role of γδ T cells in immune related adverse effects (irAEs). Both positions will be in close collaboration with
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Application deadline: All year round Research theme: Multi-scale modelling How to apply:uom.link/pgr-apply-2425 No. of positions: 1 This 3.5 year PhD project is fully funded for home students
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they release their toxic cargo to kill the cancer cells. Methods include, but are not limited to, in vitro culture of primary human cells and cell lines, organ-on-chip models, molecular biology, diverse
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supervising studies that involve in vitro assays and in vivo mouse tumor models to understand mechanisms of immunotherapy resistance, exploration of pathways involved in signal transduction in different T cell
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single mirror image forms is often denoted as “A Signature of Life”. Homochirality is essential for, e.g., molecular recognition and information processing, enzyme functioning and cell replication. However
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contribute to ongoing cancer risk modelling projects within the Centre for Cancer Genetic Epidemiology (CCGE), based in the Department of Public Health and Primary Care. They should have a strong understanding
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, tailored, complex materials such as advanced polymers or polymeric formulations, catalysts, mechatronic devices and software and algorithms. Design, control and modelling and analyses complement