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Field
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Join Dr. Marcel van den Brink’s multidisciplinary team to explore innovative ways to decipher the molecular mechanisms by which the microbiome contributes to the biology of bone marrow
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molecular and structural mechanisms is essential for therapeutic development. Using E3 activity-based chemical probes, we have substantially expanded the known landscape of E3 ligase subtypes—effectively
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. The project involves both in vitro and in vivo studies to uncover the molecular and cellular mechanisms driving cancer-associated immunosuppression using mouse and human solid tumor models. Additionally
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molecular techniques in cultured cells, xenografts, and engineered mouse models • Working with conventional laboratory reagents, instrumentation, and molecular/tissue biology techniques. • Operating and
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can successfully predict previously-unknown regulators of seed development through functional genetic analysis of conserved, uncharacterised genes in the model seed plant Arabidopsis thaliana
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, molecular dynamics, and machine learning, to model battery electrolyte and solid electrolyte interphase (SEI), while collaborating with experimentalists. Qualifications • Ph.D. in Computational Materials
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lead the in vivo functional analysis of this gene using conditional KO mouse models, with a focus on brain development, neuronal differentiation, and seizure susceptibility. All models are already
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using cancer models, molecular data analysis, and preparation of scientific publications and funding proposals. You’ll also contribute to collaborative projects and help with lab management and training
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cancer. We are particularly interested in candidates with strong molecular biology and genome editing experience who are excited to work at the interface of tumor metabolism and therapeutic resistance
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to: rhizosphere and phyllosphere microbiology microbial evolution molecular and/or structural aspects of plant-microbe or plant-fungal interactions the molecular biology of soil-dwelling bacteria or fungi