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Field
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Ubiquitin E3 ligases are central regulators of cellular proteostasis and are directly implicated in neurodegeneration. A detailed understanding of their molecular and structural mechanisms is
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Drosophila melanogaster and mammalian cells as our model systems. Our lab has pioneered innovative cell biological approaches, enabling unprecedented visualization of individual clock mRNAs, genes, and
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spectrometry, iCLIP, phase separation assays, and other molecular and cellular biology techniques. Experience in handling cell and animal models for studying RNA-related stress responses and disease mechanisms
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immediately. Responsibilities* Design and develop microphysiological systems (MPS) for tendon research Perform cell culture and molecular biology experiments Conduct mechanical testing and characterization
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development of mouse models, although this is not requisite. They will be expected to have excellent skills in molecular biology and experience in CRISPR/Cas9 genome editing. Furthermore, they will be expected
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University of North Carolina at Charlotte | Charlotte, North Carolina | United States | about 17 hours ago
at Charlotte is interested in the molecular mechanisms of genome integrity and cancer etiology using Xenopus egg extracts and mammalian cells as model systems. In particular, the Yan lab has made contributions
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Europe Marie Skłodowska-Curie Action - Doctoral Network FluxBEATS that integrates geological observations, cutting-edge geochemical and biogeochemical analyses, data and modeling, from modern volcanic
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FluxBEATS that integrates geological observations, cutting-edge geochemical and biogeochemical analyses, data and modeling, from modern volcanic systems along mid-ocean ridges and back-arc spreading centers
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utilize preclinical tumour models, high dimensional techniques including spatial mass spectrometry and immunocytochemistry, alongside complementary state-of-the-art molecular biology approaches to identify
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key cancer-fueling pathways in hormone-driven (i.e., prostate and breast) cancers. They will also assess druggability of these genes using novel inhibitory/degrader drugs in preclinical models