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molecular biology, quantitative imaging and biophysical approaches to investigate cell shape changes in cultured cells and in vivo. Current projects in the lab include investigating the regulation
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molecular biology, quantitative imaging and biophysical approaches to investigate cell shape changes in cultured cells and in vivo. Current projects in the lab include investigating the regulation
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model complexes. This research is part of a large, funded collaborative project supported by the Swiss National Science Foundation, involving partner researchers based in Germany, Switzerland, and France
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help manage and contribute to our program in ex vivo human cell biology and in vivo rodent models, focused on deciphering the cellular and molecular basis for neurodegenerative diseases, including
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supervising studies that involve in vitro assays and in vivo mouse tumor models to understand mechanisms of immunotherapy resistance, exploration of pathways involved in signal transduction in different T cell
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available to conduct research on chronic pain. Using animal pain models, behavioral tests, calcium imaging, patch-clamp, optogenetics, neuroanatomy, molecular biology, the successful candidate is expected
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, which has seen little improvement in patient survival over the past decades. Utilizing genetically engineered mouse and human glioma models, our lab investigates how glioma cells interact with the tumor
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and stem cell biology. The study investigates how APOE4 expression in endothelial cells affects oligodendrocyte progenitor cells (OPCs), using iPSC-derived 3D co-culture models. This work aims to
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supervising studies that involve in vitro assays and in vivo mouse tumor models to understand mechanisms of immunotherapy resistance, exploration of pathways involved in signal transduction in different T cell
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contribute to ongoing cancer risk modelling projects within the Centre for Cancer Genetic Epidemiology (CCGE), based in the Department of Public Health and Primary Care. They should have a strong understanding