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The laboratory of Prof. Simon Davis and Dr. Mafalda Santos at the MRC Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, is seeking a talented and motivated Postdoctoral
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polymorpha and several other non seed plant models. The post is in the group of Prof. Justin Goodrich in the Institute of Molecular Plant Sciences and will be supported by a full time Post Doctoral Research
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months. The project involves developing and applying a novel integrated platform to study the chemical molecular mechanisms and signalling consequences of reactive small-molecule metabolites in organ
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novel neuroprotective strategies. You will utilise in vivo rodent models of neurodegeneration in combination with sleep/circadian clock modulators to develop an in-depth understanding of consequences
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humanised mouse models with the same mutations as patients, all of which are currently available in the laboratory. Minimum qualifications are PhD and/or MD with expertise in molecular and cellular biology
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About the role Dr. Seaborne’s group investigates the molecular and cellular mechanisms underpinning muscle biology, in the context of health and disease, with recent attention focussing
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and under load. Multi-scale modelling based on continuum mechanics and hydrodynamics informed by experiments and molecular modelling. High-throughput data analysis and image processing using Python
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leading to cardiomyopathy. This work will be performed in primary cardiomyocytes from human iPS cells, human myocardial slices from patients and humanised mouse models with the same mutations as patients
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will be responsible for co-designing and executing research programmes related to different aspects of thymus biology employing informative experimental models and a broad range of analytical platforms
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the Wellcome Trust. The overarching objective is to understand the molecular mechanisms that underlie the long-known sex-differences in the maintenance of hearing over the life course and determine if sex