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tumours and metastases with the goal to design combinatorial therapeutic approaches. The project will involve the use of genetically complex organoid-derived transplantation mouse models of pancreatic
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million individuals has never before been possible in genetics research, not even in model organisms, and promises to transform the way we think about evolution. The student will receive broad training in
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on cell viability and DDR activation in established human cell models. The student will perform CRISPR screens to determine factors that affect resistance/sensitivity and follow these up with mechanistic
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II during transcription and how they control biogenesis of ncRNA and contribute to gene expression regulation using state-of-the-art genomic approaches (Aim 2 and 3). The lab employs several model
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manufacturing (3D printing) techniques. The purpose of the studentship is to develop a next-generation in vitro model of aged human skin to evaluate the cytocompatibility of materials used in maxillofacial
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, with experience in contemporary molecular cell biology, tumour metabolism, experimental modelling and bioinformatics as applied to translational cancer genomics, ideally within the context of childhood
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Description DC6: Molecular and tissue determinants of adverse tissue outcomes in hearing implants. Join the prestigious Marie Skłodowska-Curie Actions (MSCA) Doctoral Network SHIELD (Strategies for Healing
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Tomography (ToF-PET) offers vital functional and molecular insights for improved cancer staging, its current capabilities are often limited by the timing resolution and sensitivity of existing detector
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(ToF-PET) provides critical functional and molecular insights to improve cancer staging but is currently limited by detector timing resolution and sensitivity. Metascintillators, an emerging family of
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in genotyping, molecular biology and Drosophila work. CDN has close partnership with the Medical Research Council (MRC) and CDN researchers, together with clinical researchers from King’s, make up