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molecular genetic engineering. Scientific Background In all species that lay eggs externally - in nests, ponds, mudpiles, food or other substrates - eggs and young may face unpredictable exposure to harmful
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interactions with potential pathogens. To achieve this objective, we will use the genetically tractable model fungus Zymoseptoria tritici. This fungus also causes Septoria tritici blotch (STB) disease of wheat
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improvements of the lives of a huge number of men. Techniques and skills training During the PhD you will become an expert in a range of molecular biology, biochemistry, cell and cancer biology techniques
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automated feeders), and analyse microbiome composition using 16S rRNA and whole-genome sequencing. Statistical modelling will test for links between microbes and host development and fitness.� PROJECT
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interatomic-potentials (MLIPs), refined for molten salt mixtures hosting other nuclear material solutes. We will perform density functional theory (DFT) calculations and molecular dynamics (MD) simulations
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model, human organoid technology, cell and molecular biology, confocal microscopy and metagenomic sequence analysis. By deciphering the interactions between AIEC, the microbiome and the intestinal
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of this project is to: (i) evaluate mechanisms potentially currently limiting Pst B. vulgaris infection and, thus, sexual reproduction in the UK and (ii) use spatially explicit models to predict how (and when) Pgt
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model to resolve wheat planting strategies that can be used to safeguard biodiversity and suppress rust outbreaks. Training You will be embedded in the international and multidisciplinary Saunders Lab
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computational modelling of evolutionary dynamics to propose new therapeutic strategies for adaptive intervention Where to apply Website https://www.icr.ac.uk/study-and-careers/phds-at-the-icr/our-phd-application
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of membrane Proteins and Receptors (COMPARE).3 We will focus on FFA44 and NTSR1 as model GPCRs. Building on our groups expertise in development of covalent chemical probes5 and protein labelling methods,6 a