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PhD Studentship - EASTBIO - Functional Genomics of Host Determinants in Viral Entry and Transmission
to define proteins affecting viral entry and transmission potential. Research training: The student will gain a comprehensive training that bridges molecular biology, virology, and bioinformatics. Laboratory
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. This project will explore PrfA inhibition as an anti-Listeria strategy, building on the host group’s fundamental discoveries on the molecular mechanisms of PrfA regulation. The Vázquez-Boland group recently
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). Design and fabricate patterned surfaces optimised for enzyme immobilisation. Assess synergistic antibiofilm efficacy under static and dynamic (flow-based) biofilm models. Apply advanced microscopy, protein
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for the rapidly developing quantum technologies. Quantum-optical measurements become especially intriguing in systems such as atomic ensembles or molecular processes whose quantum nature remains unclear. These open
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invertebrate model organisms has also suggested that improved ECM function is a key means by which molecular pathways that extend longevity improve age-related health. These studies have suggested that targeting
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recombination, maintaining genetic linkage of toxin/antitoxin-like systems. As a result, these chromosomes accumulate deleterious mutations that are unaccounted for in existing gene drive models. The student will
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the genetic, molecular, cellular, and whole systems level. Cross-cutting strengths lie in our world-leading expertise in neuroplasticity, interdisciplinary neuro-immune research, high-throughput sequencing
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Alzheimer’s, Parkinson’s, motor neuron disease, and related disorders. This project aims to understand the molecular mechanisms governing ESCRT dependent aggregate clearance versus extracellular vesicle (EV
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proposals related to the themes of its two research centres. These themes include information systems and digital business, information management and modelling, business process management, digital business
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investigate new strategies to protect and regenerate nerve cells after SCI by combining molecular biology, pharmacology, and gene therapy in translational models of central nervous system repair. The work will