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stem/progenitor cell plasticity (HSPCs), and leukemic transformation. The project will use innovative 2D and 3D HSPC/MSC co-culture models, functional clonogenic and differentiation assays, bulk and
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organoids, single cell multiomics, live cell imaging, and animal models. Tasks: to actively pursue the PhD project with the aim of characterizing the molecular and functional mechanisms of epithelial
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%). The Institute of Pharmacology focuses on deciphering the molecular mechanisms that control regeneration as well as tumor initiation and progression in epithelial tissues (https://www.uni-marburg.de/en/fb20
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and organoid tissue culture models to study the LTM effects on inflammatory signaling and virus-induced carcinogenesis. Unique 3D-cell biology techniques as well as molecular biology techniques, such as
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. He/she/they will learn and apply state-of-the-art molecular and cell biology technologies established in our team, ranging from in vivo disease models to multi-omics and single cell analysis
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structure with assembly and optical properties. Your role will be to tune the molecular structure of the ligands and change ligand shell structure. Using advanced scattering and microscopy, you will study the
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, crystallization, or molecular aggregation/switching. The BEAM projects cover a wide spread of topics, including theoretical physics and chemistry work. For example, our targeted syntheses are supported by models
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modellers, molecular biologists and data scientists across IBG-3 and IBG-4 Communicate your science by presenting at conferences, publishing software and peer-reviewed publications Your Profile: Master’s
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, biophysical and bio-chemistry, theoretical chemistry and mathematics , to advance the understanding of the emergence of complexity in molecular systems. Our RTG combines science and research projects that start
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interdisciplinary research team. We study tumor evolution and immune microenvironment adaptation by combining functional genomics, experimental model systems, patient samples, and computational biology (Brägelmann et