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Generate point mutants in cell lines using CRISPR-Cas9 technology Characterize the cellular transcriptome and proteome under various conditions Phenotypic characterization of a mouse model Related activities
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on the role of epigenetic dysregulation for future clinical applications, particularly on their common Mantle cell lymphoma (MCL) model, through their French networks (LYSA, Carnot Institute CALYM) and European
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research laboratory in solid-state physics, nanoscience, molecular chemistry, and materials science. Its activities range from the synthesis of (nano)materials and molecular systems to the study and modeling
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conjugates into fluorescent nanostructures, which growth results from a combination of dynamic covalent and supramolecular processes, moving from solution studies to model lipid membranes, then live cells
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investigated. These interface models and characteristics will then be transferred to other researchers for larger-scale modelling (molecular dynamics, finite element modelling of the battery…). The post-doc
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. The position will involve the use of molecular tools to generate transgenic parasites, advanced imaging techniques and the implementation of new chemoproteomic protocols. Parasite culture, biochemistry and
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Biochemistry, Molecular/Cell Biology, and/or BioEngineering documented by peer-reviewed publications Skills in a broad range of methods in the fields of Biochemistry, Molecular/Cell Biology, and/or
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The researcher will study the potential of atto-photochemistry on organic or inorganic photoinduced reactions. He or she will use quantum chemistry and molecular dynamics methods to do so. The overall objective is
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behavior in the Phenoworld using a combination of conventional and data mining approaches as well as molecular biology techniques (RNAseq, RT-PCR, immunohistochemistry, etc) to investigate neurobiological
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Description Metabolic reprogramming is a hallmark of cancer cells. Understanding the downstream molecular consequences of these metabolic changes, among which their connections with RNA modifications