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cellular signaling remains a key challenge in biology and is at the heart of the project. The PhD student will be in charge of the molecular modelling aspects of the multi-scale approaches undertaken by
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will involve (but not be limited to) applying sophisticated mouse genetic models of cancer and conditional gene targeting, single-cell RNA-seq, spectral flow cytometry, multiplex imaging and spatial
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methodology such as Thermodynamic modelling of multi-component planetary degassing/ingassing, Molecular Dynamic simulations of silicate melts, Petrology of melting of exoplanetary mantles, and the partitioning
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of the M3i unit UPR9022 at IBMC, “Models of innate immunity in insects” at the Institute of Molecular and Cellular Biology (IBMC). Our team studies the molecular basis underlying interactions between
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-/- strain) mimicking the characteristics of AS, to evaluate the effect of DNM3OS inhibition on disease progression; (2) Cellular models to dissect the signaling pathways and molecular mechanisms underlying
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, the process of host infection remains poorly understood at the molecular level. The fd phage, which specifically infects Escherichia coli, has been used as a model for studying these viruses. This phage
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" team is located within UMR 5242, at the Institute of Functional Genomics of Lyon (IGFL). It is a multidisciplinary institute, offering interesting exposure to several system models around common themes
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for epithelioid sarcoma, by characterizing epithelioid sarcoma models through state-of-the-art sequencing and molecular profiling techniques. The successful candidate is expected to develop experimental approaches
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, Birkbeck), the Protim proteomics platform, and the HPC Jean-Zay supercomputer (GENCI). Title Deciphering the molecular mechanisms of substrate recruitment in the Type IV Secretion System using
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supervised by Nadine Laguette (Institute of Molecular Genetics of Montpellier – IGMM, Montpellier). The Institute of Molecular Genetics of Montpellier (IGMM) is a joint research unit of the CNRS and the