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for months, years, or even millennia. Our lab aims to resolve the molecular mechanisms behind this process, focusing on how promiscuous enzymes (un)intentionally transform cellular metabolites into degradation
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question: « what makes our brain human ? » (Vanderhaeghen and Polleux, Nat. Rev. Neurosci. 2023). We combine cutting-edge approaches such as pluripotent stem cell models of human corticogenesis, human-mouse
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question: « what makes our brain human ? » (Vanderhaeghen and Polleux, Nat. Rev. Neurosci. 2023). We combine cutting-edge approaches such as pluripotent stem cell models of human corticogenesis, human-mouse
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temperature signalling in plants, such as the model plant Arabidopsis thaliana and the crop plants wheat and soybean. To unravel this, we focus on dynamic changes in protein phosphorylation status, since
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their expertise together to establish neural organoid models recapitulating aspects of neural-microglia interactions in neurodegenerative diseases at Ghent University. About the project MINDFUL: Lipid accumulation