97 molecular-modeling-or-molecular-dynamic-simulation Fellowship positions at Nature Careers
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emerging areas of interest, Birmingham is a dynamic place to work. We have ambitious plans to expand our research activity and are in an exciting period of growth: major investment from the University has
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resting conditions. The researcher will use a combination of synovial tissue organoid systems and transgenic mouse models to delineate the role of the proteoglycan-4 (the gene that encodes lubricin) in
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part of a dynamic research environment focusing on the early mechanisms of neurodegeneration in Parkinson’s disease. The main tasks involve working with mouse models of Parkinson’s disease. Key
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transduction and orthotopic animal models. Previous experience with CARTs, molecular cloning and animal models is essential. The post holder will join a team of scientists at ICH as well as linking with
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lavage samples – phenotypic, functional and molecular biology assays. Analyse and interpret data. Apply knowledge in a way which develops new intellectual understanding. Disseminate research findings in
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will: · Have experience and knowledge of human and murine immunology, selection tools for predicting immunologic epitopes complementing virology skills (poxvirus molecular biology
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model of flare vs remission with a 50% relapse rate. Initial data analysis has taken place using the 10x Chromium single cell sequencing identifying putative cellular subpopulations that determine
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to: rhizosphere and phyllosphere microbiology microbial evolution molecular and/or structural aspects of plant-microbe or plant-fungal interactions the molecular biology of soil-dwelling bacteria or fungi
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toxicities, neuron-glia interactions, genetics and epigenetics will provide insights in identifying novel biomarkers and drug targets. Expand and improve skills: disease models based on genome-modified animals
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, innovative sequencing and bioinformatics technologies including single cell and spatial transcriptomics, molecular biology approaches using cell-based and animal models, and biomarker studies from patients