15 molecular-modeling-or-molecular-dynamic-simulation PhD positions at University of Cambridge in United Kingdom
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Cambridge Institute (CRUK CI), to investigate the molecular mechanisms of small RNA-mediated chromatin silencing. As a whole, the Hannon laboratory has broad interests that range from discovery research
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: Advanced molecular and protein analysis Mass spectrometry-based imaging Multi-omics technologies Preclinical cardiometabolic animal models They will also gain professional development in data stewardship
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on cell viability and DDR activation in established human cell models. The student will perform CRISPR screens to determine factors that affect resistance/sensitivity and follow these up with mechanistic
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tumours and metastases with the goal to design combinatorial therapeutic approaches. The project will involve the use of genetically complex organoid-derived transplantation mouse models of pancreatic
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dynamics and tissue morphogenesis during embryo development using cellular, molecular and mechanical approaches. Cell movements underlie tissue patterns and shapes. Using chick embryos as the model system
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of these factors. The work will involve genomic, proteomic and molecular approaches to decipher how these proteins contribute to NEPC and to explore if they can be therapeutically blocked. We aim to understand how
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have or expect to obtain a first or upper second-class degree in a relevant subject from a UK university, or equivalent standard abroad. Prior research experience, for instance in molecular biology
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formation, dynamics and functions of four-stranded DNA G-quadruplex structures and modified DNA bases in the genome (e.g. see Genome Biology, 2025 25, 155; Nature Chemistry, 2025, 17, 875; PNAS, 2024, 12(7
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to symmetry breaks in the patterning process. A hybrid modelling approach integrating the dynamics of a core network while utilising a virtual template from experiments for cellular growth and division will be
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of Cambridge Department of Medicine Molecular Immunity Unit, housed within the MRC Laboratory of Molecular Biology. Shortlisted candidates will be invited to visit the institute to deliver a seminar and