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Cambridge Institute (CRUK CI), to investigate the molecular mechanisms of small RNA-mediated chromatin silencing. As a whole, the Hannon laboratory has broad interests that range from discovery research
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formation, dynamics and functions of four-stranded DNA G-quadruplex structures and modified DNA bases in the genome (e.g. see Genome Biology, 2025 25, 155; Nature Chemistry, 2025, 17, 875; PNAS, 2024, 12(7
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dynamics and tissue morphogenesis during embryo development using cellular, molecular and mechanical approaches. Cell movements underlie tissue patterns and shapes. Using chick embryos as the model system
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understood. This project will combine molecular, cellular, and physiological approaches to explore how exercise reprograms metabolic and inflammatory pathways that connect cardiac function to systemic health
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screens. Nature Reviews Molecular and Cell Biology 2023. 24, 477-494. Awwad, S.W., Doyle, C., Coulthard, J., Bader, A.S., Gueorguieva, N., Lam, S., Gupta, V., Belotserkovskaya, R., Tran, T-A
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-sequencing, flow cytometry, multiplex immunofluorescence, and standard molecular biology and biochemistry techniques. A computational component may also be available, depending on the skills and preference
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to symmetry breaks in the patterning process. A hybrid modelling approach integrating the dynamics of a core network while utilising a virtual template from experiments for cellular growth and division will be
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molecular biology. Relevant post-doctoral experience is desirable. High quality peer-reviewed publications and a keen interest in translational regulation are essential. If you have an excellent background in
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of Cambridge Department of Medicine Molecular Immunity Unit, housed within the MRC Laboratory of Molecular Biology. Shortlisted candidates will be invited to visit the institute to deliver a seminar and
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prostate cancer risk across diverse ethnic groups. This work aims to support more equitable risk stratification in cancer screening programmes. Using simulations based on multistate modelling framework