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understanding the drivers of cancer spread. We focus on characterising the dynamic behaviour of tumour cells within distinct metastatic niches. Building on our experience in cell-fate tracking tracking and
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datasets is a plus. We offer you A fully-funded PhD position for four years in a dynamic research group with an excellent research infrastructure in the international and interdisciplinary Department
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)chemistry, biotechnology, biophysics, or a related discipline. Experience with molecular cloning, protein expression, purification, and characterization, biocatalysis, as well as high-throughput screening
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Your position Biomolecular dynamics, such as conformational changes, are the understudied link between biomolecular structure and function. Single-molecule FRET is an established technique, unique
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, for advancing our fluorescence-based DyeCycling/FRET technology to study biomolecular dynamics. Biomolecular dynamics, such as conformational changes, are the understudied link between biomolecular structure and
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were involved in (e.g. your MSc project) stating its rationale, major outcome and your contribution (max. half a page); a CV; a copy of your MSc degree, and the contact details of 3 references including
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enables label-free trapping and sensing of single proteins in solution for up to hours. Now, we leverage the unique abilities of nanopore trapping to detect proteins and their conformations, dynamics
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. Utilized methods include molecular and cell biology, flow cytometry, histology and microscopy, protein work, and bioinformatics. Your profile We are looking for candidates who enjoy lab work and who also
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in solution for up to hours. Now, we leverage the unique abilities of nanopore trapping to detect proteins and their conformations, dynamics, interactions, catalytic mechanisms etc. in real-time
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research in a dynamic, innovative scientific working environment. Conditions of employment and salary are governed by the personnel and salary regulations of the University of Basel. Application / Contact