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expression, purification and mutagenesis and liposome reconstitution, respirometic studies with isolated mitochondria), and biophysical methods to study protein dynamics, conformations and molecular
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is a multidisciplinary research lab, providing the opportunity to develop extensive skills in a breadth of areas, including plant pathology, molecular biology, and computational biology. Whilst
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dynamics, and evolutionary adaptability compared to sexual reproduction in natural (wild) plant populations. We will address two questions: (1) Does apomixis act as a transitional “safety net” mechanism post
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Cambridge Institute (CRUK CI), to investigate the molecular mechanisms of small RNA-mediated chromatin silencing. As a whole, the Hannon laboratory has broad interests that range from discovery research
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aesthetic appeal. Since the first synthesis of a catenane in 1960, mechanical bonds have been used in a variety of contexts and their dynamic properties have been exploited to build molecular machines and new
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scattering with computer modelling such as molecular dynamics simulations and AI-assisted data mining. The new technical capabilities will help bridge the current gap in biocide development, i.e., to link
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Scientific Researcher Salary £40,832 per annum Fixed term, 12 months MRC Laboratory of Molecular Biology, Cambridge, UK An opportunity is available for a Scientific Researcher to join the group
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of these factors. The work will involve genomic, proteomic and molecular approaches to decipher how these proteins contribute to NEPC and to explore if they can be therapeutically blocked. We aim to understand how
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formation, dynamics and functions of four-stranded DNA G-quadruplex structures and modified DNA bases in the genome (e.g. see Genome Biology, 2025 25, 155; Nature Chemistry, 2025, 17, 875; PNAS, 2024, 12(7
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in genotyping, molecular biology and Drosophila work. CDN has close partnership with the Medical Research Council (MRC) and CDN researchers, together with clinical researchers from King’s, make up