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Ubiquitin E3 ligases are central regulators of cellular proteostasis and are directly implicated in neurodegeneration. A detailed understanding of their molecular and structural mechanisms is
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is a dynamic, supportive and highly collaborative research group which studies how common genetic variation influences the human immune system and how this can predispose to autoimmune and inflammatory
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those leading to dementia and neuroinflammation. We have a strong focus on mechanistic dissection of genetic, molecular cellular and neuropathological processes which underlie across the neurodegeneration
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emerging areas of interest, Birmingham is a dynamic place to work. We have ambitious plans to expand our research activity and are in an exciting period of growth: major investment from the University has
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perivascular cells of the neurovascular unit/perivascular niche, and on brainvascular heterogeneity in development, health and disease: The main aims are: i) to understand the cellular and molecular
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a highly motivated postdoctoral researcher to join our dynamic group investigating mitochondrial genetics and function (http://themalab.co.uk ). The candidate will mainly use genetic and biochemical
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. Experience with the tools of bioinformatics, molecular biology and/or nucleic acid biochemistry is essential. You should be eager to learn new skills and systems, and should have effective communication
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testbeds to explore new and emerging areas of interest, Birmingham is a dynamic place to work. We have ambitious plans to expand our research activity and are in an exciting period of growth: major
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, clinical applications, addressing cancer’s social determinants, lowering barriers to UK SMEs, catalysing innovation and positioning the UK as a global leader in the dynamic healthcare and AI ecosystem. About