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2026 or as soon possible. Job description This position will involve designing, conducting, and analysing experiments to understand the impact of inflammation on the gut-brain axis in the zebrafish model
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preclinical in vitro and in vivo models Supervise and mentor MSc/MD/PhD students Collaborate with national and international research partners Present your results at scientific meetings Publish your findings
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pathogens as a model system. There are two post-doctoral research positions and one PhD studentship associated with Dr. McDonald’s UKRI Future Leader Fellowship, which will explore the cell biology
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experimental systems, ranging from molecular screening tools, state-of-the-art methods for molecular/cellular characterization, animal models, and primary human cell/organoid models. We offer a unique
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from correcting disease-causing mutations, the potential of introducing protective mutations will be explored. These strategies will be evaluated on cellular and mouse disease models, in order to
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immune cells will be studied in preclinical models with special emphasis on how adoptively transferred cells interact with tumor cells, the tumor microenvironment, and resident immune cells. Successful
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mature into fully independent researcher. Successful candidate will gain an experience in genome wide technology, CRISPR-Cas editing, mouse models and stem cell biology. Applicants should have a Ph.D. and
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) as models. PXR and CAR transcriptionally regulate cytochrome P450 3A4 (CYP3A4) and CYP3A5-drug-metabolizing enzymes that metabolize more than 50% of clinical drugs, the dysregulation of which
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available single-cell sequencing data generated from patient samples and mouse models, we will enhance and apply machine-learning based algorithms to deconvolute bulk tumor RNA-seq samples to distinct immune
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studies by cryo-electron microscopy (cryo-EM) and/or X-ray crystallography. Perform data processing and model building (e.g., Relion , CryoSPARC , Coot, PyMOL ). Option 2 : Cell Biology Design and execute