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on the development of anti-infective drugs and vaccines using the pig as a model platform. Main tasks will include the design, coordination, and execution of pig experiments, and assessment of drug and vaccine
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. In particular we use the promiscuous pregnane X receptor (PXR) and constitutive androstane receptor (CAR) as models. PXR and CAR transcriptionally regulate cytochrome P450 3A4 (CYP3A4) and CYP3A5-drug
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modelling are an advantage. Documented experience in classroom teaching is a benefit. You will be driving the organic chemistry aspects of two projects. You will collaborate with research groups from
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contexts. Additional experience in industrial ecology, material flow analysis, and in particular energy systems modelling, simulation, and mobility will be considered a strong asset. The candidate shall be
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us. Gender equality is an important aspect for us. To support work life balance we offer flexible working hours, variable part-time, job-sharing models and participation in mobile work (up to 50%). You
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are seeking a motivated and enthusiastic colleague with strong computational skills in the analyses of complex data sets to join our teams. About the project We have generated advanced brain on chip models
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electrophysiology to translational models, including animal studies and analyses of human tissue samples. This full-stack methodology enables us to directly link molecular channel function with disease phenotypes
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(multiomics), CRISPR genome editing, deep learning, network modeling, confocal and two-photon live imaging. Please visit the Özel Lab Website for more information. Ideal candidates will be highly motivated and
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tendon models ("tendon-on-chip"), this will provide a powerful system to investigate the complex mechanobiology of tendons. Particular focus will be given to neurotendinous crosstalk and its
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transduction, cell culture, and immune functional assays; supporting the development of in vivo models, such as adoptive T-cell transfer in mice, for preclinical testing of engineered circuits where relevant