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-scale screens to study fundamental principles in molecular and complex trait genetics using microbes as model systems. Our core technology MAGESTIC (https://doi.org/10.1038/nbt.4137 ), a CRISPR/Cas9-based
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tendon models ("tendon-on-chip"), this will provide a powerful system to investigate the complex mechanobiology of tendons. Particular focus will be given to neurotendinous crosstalk and its
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proteomic analyses often obscure the intricate cellular and molecular variations within this complex environment. Single-cell proteomics (SCP) offers a novel approach to dissect this heterogeneity by
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) Cardiac development or disease. We are interested in applicants with strong interest in using the mouse as a model for human genetic diseases Research focus: Our lab investigates cell fate progression
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electrophysiology to translational models, including animal studies and analyses of human tissue samples. This full-stack methodology enables us to directly link molecular channel function with disease phenotypes
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mice as model systems and combine molecular, cellular, developmental and bioinformatics approaches to establish how chromatin regulators reshape the epigenome and regulate cell fate during development
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are seeking a motivated and enthusiastic colleague with strong computational skills in the analyses of complex data sets to join our teams. About the project We have generated advanced brain on chip models
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Performs a variety of moderately complex research tasks determined by the field and scope of the particular research project/study. Performs tasks related to the research project independently, but
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performing simulations with computational models of the Earth system on different levels of complexity scientific publication records appropriate for the experience level experience in scientific software
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pathways driving leukemic transformation during haematopoietic development. The successful candidate will use in vitro differentiation systems (ESC/iPSC) to model normal and malignant haematopoiesis